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Skin cartoon2/2/2024 Genetics also influence the natural skin contour and color for example, people of African-American descent typically exhibit thicker and more lustrous skin compared to people of Anglo-Saxon ancestry. For example, a person with an occupation requiring much outdoor exposure to the sun and ultraviolet radiation will tend to show premature skin aging signs sooner than a person working indoors. Genetic and environmental factors also affect skin thickness. The skin begins to thin again during the fifth decade of life, primarily due to changes in the dermis with loss of epithelial appendages, elastic fibers, and ground substance, among others. Children have thin skin, which gradually thickens until the fourth decade of life, affected by the concentration of sex steroids, general health, and hydration. Primarily due to the effects of androgens, adult males typically have thicker skin than females in most areas of the body. Thinner skin is present on eyelids, axillae, genitals, and the mucosal surfaces exposed to the external environment, such as oral mucosa, vaginal canal, and other selected internal body surfaces. Thick skin is present on the palms and soles, where there is marked keratinization and the stratum lucidum layer. The varying thickness is due to changes in the dermis and epidermis. The thickness of skin varies based on its location, age, gender, medications, and health affecting the skin’s density and thickness. The multiple layers of the skin are dynamic, shedding and replacing old inner layers.
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